Indications
Peloxin M Tablet is used for:
Susceptible infections, Gonococcal urethritis, Acute uncomplicated cystitis
Adult Dose
Oral
Susceptible infections
Adult: 400 mg bid.
Acute uncomplicated cystitis in women; Gonococcal urethritis in men
Adult: 800 mg as single dose.
IV Influsion
Adult: 400 mg in 100 or 250 ml of 5% dextrose slow infusion over an hour bid.
Child Dose
Renal Dose
Renal impairment: Dose reduction may be necessary.
Administration
Should be taken with food. Take w/ meals.
Contra Indications
Hypersensitivity to quinolones, children <12 yr, pregnancy, lactation.
Precautions
Underlying CNS disease; hepatic disease; renal impairment. Avoid sun exposure, may cause severe sunburn.
Pregnancy-Lactation
Interactions
Reduced absorption with antacids, didanosine (DDI), iron salts, pirenzepine, sucralfate, vincristine, zinc salts; increased levels with cimetidine, probenecid, theophylline; increases the levels of cyclosporine; causes seizures with foscarnet, NSAIDs, piroxicam; hypoglycemia with glimeperide; antagonistic with quercetin.
Side Effects
Side effects of Pefloxacin :
Nausea, vomiting, gastric pain, dizziness, insomnia, allergic skin reactions, thrombocytopaenia, leukopenia/neutropenia, photosensitisation, arthropathy, muscular pain, headache, delusions, depression, hallucinations, hepatic dysfunction.
Mode of Action
Pefloxacin is a fluoroquinolone antibacterial that exhibits its bactericidal action by inhibition of DNA gyrase and topoisomerase IV which are needed for bacterial DNA reproduction.
Note
Peloxin M 400mg Tablet generic name is Pefloxacin. Peloxin M 400mg Tablet is manufactured by Pharmadesh Laboratories Ltd.Peloxin M is availble in all over Bangladesh.
Mes BD drug index information on Peloxin M Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.