Eflornithine Hydrochloride Monohydrate
Indications
Eflornithine Hydrochloride Monohydrate is used for:
Reduction of Facial Hair in Women
Adult Dose
Topical
Reduction of Facial Hair in Women
Apply to affected area twice daily at least 8 hours apart
Child Dose
Topical
Reduction of Facial Hair in Women
>12 years: Apply to affected area twice daily at least 8 hours apart
Renal Dose
Administration
Contra Indications
Hypersensitivity
Precautions
Discontinue if sensitivity occurs
Lactation: Not known whether distributed into breast milk; use caution
Pregnancy-Lactation
Interactions
Side Effects
Side effects of Eflornithine Hydrochloride Monohydrate :
Acne, Pseudofolliculitis barbae, Burning, Stinging, Dry, and/or tingling skin, Erythema, Anorexia, Neutropenia, Rash, Pruritus, Alopecia
Mode of Action
May inhibit ornithine decarboxylase (ODC), an enzyme that catalyzes biosynthesis of intracellular polyamines required for cell division & differentiation, which in turn can affect hair growth